Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. For example, gene therapy could help people with narcolepsy to produce sleep-regulating proteins. As such, gene therapy may be another avenue for future treatments. Genetic factors may play a role in the development of narcolepsy. For example, hypocretin may influence the development of narcolepsy, so researchers are investigating whether manipulating these cells can treat narcolepsy. Researchers are investigating several experimental medications to help with narcolepsy. They also highlight the importance of taking safety precautions, particularly when driving. avoiding caffeine and alcohol, if applicable.maintaining a regular bedtime and waking time.taking short naps during the day and scheduled intervals.NINDS suggests several lifestyle changes that can help people with narcolepsy to maintain alertness during the day and sleep better at night. These treatments will depend on several factors, including the person’s age, tolerance to medications, and the severity of the disease. Doctors may also prescribe other treatments alongside or sometimes instead of medications. Medications are an important way of treating excessive daytime sleepiness and cataplexy in people with narcolepsy. Research suggests that solriamfetol is similarly effective to modafinil in treating daytime sleepiness. Solriamfetol: Available as the brand-name drug Sunosi, solriamfetol is a dopamine-norepinephrine reuptake inhibitor that can help reduce daytime sleepiness.Examples include methylphenidate and dexamfetamine. However, they can be addictive and cause several side effects, such as nervousness and heart rhythm disruptions. These powerful stimulants can alleviate daytime sleepiness. Amphetamine-like stimulants: Doctors may prescribe amphetamine-like stimulants where modafinil is not effective.Armodafinil: This is a similar medication to modafinil that can also improve wakefulness.Modafinil can increase alertness and reduce daytime tiredness. Doctors typically prescribe this medication first because it is less addictive and has fewer side effects than other stimulants. Modafinil: Available as the brand-name drug Provigil, modafinil is a first-line prescription medication that stimulates the central nervous system (CNS).Doctors may prescribe medications to address this symptom, such as: Share on Pinterest Guido Mieth/Getty ImagesĮxcessive daytime sleepiness is a major symptom of narcolepsy that can be highly disruptive to daily life. In this article, we discuss the types of medication someone with narcolepsy might take, as well as other available treatments. This reduces symptoms of the condition and improves people’s quality of life. The goal of treatment is to increase daytime alertness and reduce sleep disruptions at night. People with narcolepsy typically require medication to manage their condition and maintain a regular lifestyle. People with this form of the condition have a typical level of hypocretin, and the cause of the condition is unclear. A low level of hypocretin is a possible cause of this condition, which is a brain chemical for regulating sleep. Type 1 causes cataplexy with the other symptoms. There are two primary types of narcolepsy. The disruptions to sleep patterns can cause additional problems, such as depression, fatigue, and overeating.
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